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Deferiprone binds to iron and removes it from the bloodstream. Deferiprone is used to treat iron overload caused by blood transfusions in people with certain hereditary red blood cell disorders (thalassemia syndrome).
Deferiprone is part of the Metal Chelators class and treats Iron Overload. Metal chelators are used to treat excesses of metal in the body in conditions like Wilson's disease and iron overload. They work by binding to the metal and removing it from the body. Deferiprone is only available as a generic drug. Compare metal chelators.
Deferiprone is an orally active iron-chelating agent used in the management of transfusion-related hemosiderosis. It has been in clinical use for over 20 years and is effective in reducing cardiac iron load and improving cardiac function. As cardiac siderosis is the leading cause of death in patients with transfusion-dependent thalassemia, deferiprone helps to improve the overall prognosis of these patients.
It is relatively well tolerated with gastrointestinal symptoms being the most typical side effects. Agranulocytosis (0.5%), neutropenia (9%), thrombocytopenia (up to 45%), and arthropathy (20%) are the most critical side effects and may require discontinuation of therapy. Regular monitoring of blood counts is recommended for patients on deferiprone therapy.
Deferiprone binds to iron and removes it from the bloodstream. Deferiprone brands in India are used to treat iron overload caused by blood transfusions in people with certain hereditary red blood cell disorders (thalassemia syndrome). Deferiprone may also be used for purposes not listed in this medication guide.
Take this medicine by mouth. Follow the directions on the prescription label. Use the special measuring cup that comes with this medicine to measure your dose. Household spoons are not accurate. After taking your dose, add about 10 to 15 mL of water to the measuring cup and swirl it around to mix the water with any remaining medicine in the bowl, and drink the mixture.
Avoid taking this medicine within 4 hours of foods, mineral supplements, or antacids that contain iron, aluminum, or zinc. You can take this medicine with or without food. If it upsets your stomach, take it with food. Take your doses at regular intervals. Could you not take it more often than directed? Do not stop taking except on your doctor's advice.
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